Semaglutide
A long-acting GLP-1 receptor agonist and the most heavily studied peptide in modern metabolic medicine.
- Evidence
- AStrong Clinical Evidence
- Regulatory status
- FDA Approved for Specific Indication
Search by name, research area or evidence grade. Each guide explains what is known, what is only preclinical, and what remains unknown.
35 of 35 entries
A long-acting GLP-1 receptor agonist and the most heavily studied peptide in modern metabolic medicine.
A dual GIP and GLP-1 receptor agonist that produced the largest weight reductions seen in a completed obesity phase 3 programme at the time of publication.
An investigational triple incretin agonist that produced very large weight reductions in phase 2 research.
A long-acting amylin analogue studied alone and in combination with semaglutide.
A daily GLP-1 receptor agonist and the reference point against which newer incretin drugs are measured.
A growth hormone fragment once developed for obesity, with disappointing human results.
A small-molecule NNMT inhibitor discussed alongside peptides, with no human evidence base.
The most discussed recovery peptide in wellness culture, and one of the clearest examples of a preclinical evidence base being read as clinical proof.
A synthetic fragment related to thymosin beta-4, studied in animal wound-healing models.
A naturally occurring copper-binding tripeptide with the strongest evidence in topical skin research.
A long-acting growth hormone releasing hormone analogue with published phase 1 human data and no outcome evidence.
A selective growth hormone secretagogue often paired with GHRH analogues in community protocols.
The shortest active fragment of GHRH, historically approved and used diagnostically.
A stabilised GHRH analogue and the clearest example of a growth hormone axis peptide passing full regulatory review.
A four-amino-acid peptide central to longevity marketing and unsupported by modern controlled evidence.
A mitochondrial-derived peptide studied in exercise physiology and metabolic regulation.
A cardiolipin-targeting mitochondrial peptide that has reached genuine clinical trials, with mixed outcomes.
A synthetic ACTH fragment analogue used clinically in Russia and unapproved elsewhere.
A tuftsin-derived peptide studied for anxiety in Russian clinical research.
A nonapeptide isolated from rabbit brain in the 1970s, still discussed for sleep despite inconsistent evidence.
A melanocortin receptor agonist approved for a narrowly defined sexual desire disorder.
An unregulated tanning peptide with documented case-report harms and no approval.
An immunomodulatory thymic peptide with real clinical trial data and approvals outside the US.
The anti-inflammatory C-terminal tripeptide of alpha-MSH, studied in gut inflammation models.
Synthetic gonadotropin-releasing hormone, used diagnostically and increasingly in compounded hormonal practice.
An early growth hormone releasing peptide with pronounced appetite effects and no approved use.
The body's principal intracellular antioxidant tripeptide, widely supplemented and modestly evidenced.
A central metabolic coenzyme studied for mitochondrial function and ageing biology, usually supplied as a 500 mg lyophilised research vial.
A 28-amino-acid signalling peptide with vasodilatory and immunomodulatory activity, studied clinically as aviptadil and used intranasally in research contexts.
A short synthetic tripeptide from Russian peptide research, studied in cell models of cartilage and connective tissue, with no human trial data.
A combination research vial pairing a long-acting GHRH analogue with a selective ghrelin receptor agonist, commonly supplied as 10 mg of each.
A combination research vial pairing two peptides studied in animal models of tissue repair, commonly supplied as 10 mg of each.
A three-component research blend of GHK-Cu, BPC-157 and TB-500, typically supplied as a 70 mg vial and discussed in skin and tissue research contexts.
A four-component research blend adding KPV to the GHK-Cu, BPC-157 and TB-500 combination, typically supplied as an 80 mg vial.
A combination research vial pairing two Russian nootropic and anxiolytic peptides, commonly supplied as 10 mg of each.