The Longevity Evidence Gap
Lifespan claims require lifespan data. Almost nothing marketed for longevity has any.
Human lifespan studies are structurally difficult: they take decades, cannot be blinded indefinitely, and require enormous samples. This is why the longevity field relies on surrogate markers.
Surrogates are legitimate research tools and poor marketing evidence. A change in a biomarker is a hypothesis about outcomes, not a demonstration of them.
Epitalon as a case study
Epitalon's reputation rests on a regional research tradition with limited independent replication and reporting that cannot be appraised against modern standards. That earns grade E — not because the idea is absurd, but because the evidence is not there.
This article is educational and is not medical advice. It does not recommend or provide individualised dosing. Speak with a qualified healthcare professional about your own health.