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Laboratory Practice

How to Read a Certificate of Analysis

A COA is only as good as the batch number, the laboratory name and the date printed on it.

Peptide Atlas EditorialJune 26, 2026 · 6 min read

A certificate of analysis reports what a laboratory measured in a specific sample. Four fields determine whether it means anything: what was tested, who tested it, when, and which batch.

Identity and purity are different tests

Mass spectrometry answers whether the molecule is what it claims to be. HPLC answers what proportion of the sample is that molecule. A document showing only one answers only half the question.

Batch matching

A certificate for a different batch than the vial in hand is documentation of something else. Batch identifiers should match exactly.

This article is educational and is not medical advice. It does not recommend or provide individualised dosing. Speak with a qualified healthcare professional about your own health.